Ocular syphilis masquerading as bilateral peripheral ulcerative keratitis

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Ocular syphilis masquerading as bilateral peripheral ulcerative keratitis

Ocular syphilis has varied manifestations in the eye. Peripheral ulcerative keratitis (PUK) is a crescent-shaped ulcer involving the peripheral cornea and associated with thinning. PUK is caused by both autoimmune and infectious diseases, such as rheumatoid arthritis, tuberculosis, and herpes. Here, we report a rare case of bilateral PUK caused by syphilis. A 55-year-old man presented with recu...

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Role of ocular matrix metalloproteinases in peripheral ulcerative keratitis.

AIM Peripheral ulcerative keratitis (PUK) is an ocular manifestation of rheumatoid arthritis and other similar systemic diseases. The purpose of this inquiry was to investigate the involvement of matrix metalloproteinases (MMPs) in the induction and/or maintenance of PUK. METHODS Substrate gel electrophoresis was used to characterise the MMP activities secreted by primary cultures of keratocy...

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Update on peripheral ulcerative keratitis

Ulcerative inflammation of the cornea occurs in the perilimbal cornea, and is associated with autoimmune collagen vascular and arthritic diseases. Rheumatoid arthritis is the most frequent underlying disease. The tendency for peripheral location is due to the distinct morphologic and immunologic characteristics of the limbal conjunctiva, which provides access for circulating immune complexes to...

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Congenital Syphilis Masquerading as Leukemia

As of late, the incidence of congenital syphilis in the United States is increasing. Each new case represents a failure of preventing, diagnosing, and treating syphilis in pregnant women. Pediatricians should confirm that all women have received adequate screening for and management of syphilis during pregnancy. Congenital syphilis is easily treatable but may be a diagnostic challenge with high...

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Peripheral ulcerative keratitis (PUK) is an immune-mediated disorder characterized by patchy, peripheral stromal thinning and infiltrates which tend to coalesce and extend to the limbus and often the sclera (unlikeMooren's ulcer) even in the presence of an intact overlying epithelium [1]. PUK is usually associated with systemic disorders such as rheumatoid arthritis, inflammatory bowel disease,...

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ژورنال

عنوان ژورنال: Taiwan Journal of Ophthalmology

سال: 2016

ISSN: 2211-5056

DOI: 10.1016/j.tjo.2016.06.002